About 11 results found for searched term "Tryptophan Hydroxylase" (0.201 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M3538 | Telotristat Etiprate | Tryptophan Hydroxylase |
| LX 1606 Hippurate | ||
| Telotristat Etiprate (LX 1606 Hippurate) is an orally bioavailable, tryptophan hydroxylase (TPH) inhibitor with potential antiserotonergic activity. | ||
| M5369 | Fenclonine (4-Chloro-DL-phenylalanine) | 5-HT Receptor |
| PCPA; CP-10188; 4-Chloro-DL-phenylalanine; p-Chlorophenylalanine | ||
| Fenclonine (4-Chloro-DL-phenylalanine) is a selective and irreversible inhibitor of tryptophan hydroxylase, a rate-limiting enzyme in the biosynthesis of serotonin. Fenclonine (4-Chloro-DL-phenylalanine) acts pharmacologically to deplete endogenous levels of serotonin. | ||
| M8913 | Telotristat ethyl | Tryptophan Hydroxylase |
| LX1606 | ||
| Telotristat ethyl, also known as LX1606, is an oral serotonin synthesis inhibitor or peripheral tryptophan hydroxylase (TPH) inhibitor. | ||
| M14540 | LP-533401 | Others |
| LP-533401 is a Tryptophan hydroxylase 1 inhibitor that regulates serotonin production in the gut. | ||
| M14541 | LP-533401 hydrochloride | Others |
| LP-533401 hydrochloride is a tryptophan hydroxylase 1 inhibitor that regulates serotonin production in the gut. | ||
| M14542 | LX-1031 | Tryptophan Hydroxylase |
| LX-1031 is a potent, orally available tryptophan 5-hydroxylase (TPH) inhibitor that reduces serotonin (5-HT) synthesis peripherally. | ||
| M14543 | PCPA methyl ester hydrochloride | Others |
| 4-Chloro-DL-phenylalanine methyl ester hydrochloride | ||
| PCPA methyl ester hydrochloride (4-Chloro-DL-phenylalanine methyl ester hydrochloride), a reversible tryptophan hydroxylase inhibitor, is a serotonin (5-HT) synthesis inhibitor. | ||
| M21499 | Rodatristat ethyl | Others |
| KAR5585 | ||
| Rodatristat ethyl (KAR5585) was a first-in-class inhibitor of tryptophan hydroxylase 1 (TPH1) with oral activity. | ||
| M27679 | Telotristat | Tryptophan Hydroxylase |
| LP-778902 | ||
| Telotristat (LP-778902) is a potent tryptophan hydroxylase inhibitor with an in vivo IC50 of 0.028 μM. | ||
| M28796 | Rodatristat | 5-HT Receptor |
| KAR5417 | ||
| Rodatristat (KAR5417) is a potent tryptophan hydroxylase 1 (TPH1) and TPH2 inhibitor with IC50s value of 33 nM and 7 nM, respectively, and shows robust reduction of intestinal serotonin (5-HT) levels in mice. | ||
| M28854 | ACT-678689 | Tryptophan Hydroxylase |
| ACT-678689 (Compound Example 1.53.4) is a tryptophan hydroxylase (TPH) inhibitor with an IC50 of 8 nM. | ||
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